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what virus causes paget's disease. The exact cause of Paget s disease remains uncertain. There is also thought to be a genetic link for Paget s disease with a possible autosomal dominant inheritance. Although the cause is unknown, genetics may play a role because the disease sometimes runs in families. Research suggests a slow-growing virus may trigger  Key words Paget s disease, osteoclast, canine distemper virus, Paramyxovirus, tions cause a predisposition to Paget s disease, but that. Although the cause of Paget s disease is unknown, there is much evidence to This led to the hypothesis that Paget s disease may be due to a slow-virus   Paget s disease is a rare disorder of the bone affecting the rate of formation and Genes are said to be activated when exposure to a virus. unknown viral cause proposed up to 40 have a relative w/disorder men affected twice as much chronic skeletal bone disorder excessive  Paget s disease of bone most commonly occurs in the pelvis, skull, spine and legs. Even though they are They think that a virus may cause it in some cases. results in some people becoming more susceptible to the changes caused by the virus and later developing Paget s disease. Paget s disease may occur in more  Paget disease causes an increase in vascularity of the affected bones, causing the skin temperature to rise. Elderly patients or those with large, What causes Paget s disease The cause of Paget s disease is unknown. Research findings suggest that Paget s disease may be caused by a slow virus   This focal disorder of aging bone may be asymptomatic or cause pain, bowing An elevated serum alkaline phosphatase level may signal Paget disease, but Although there is good evidence that measles and canine distemper virus can  cause Paget s disease and additional susceptibility loci or environmental factors the measles virus nucleocapsid gene (MVNP) in osteoclasts induces pagetic-  This page includes the following topics and synonyms Pagets Disease of Bone, Pagets Aka Paget s Disease of Bone, Paget s Disease, Osteitis Deformans Osteoporosis Secondary Causes · Metabolic Bone Disease Following ICU Viral antigen association (especially Measles) Family History (Chromosome 18q).

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